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RecruitingKartagener Syndrome

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease

Eligible age

All ages

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The overall short-term goals of this project include the following: 1) identify the genes that are key to the function of respiratory cilia to protect the normal lung; and 2) the effects of genetic mutations that adversely affect ciliary function and cause primary ciliary dyskinesia (PCD), which results in life-shortening lung disease. The long-term goal of this project is to develop better understanding of the underlying genetic variability that adversely modifies ciliary function, and predisposes to common airway diseases, such as asthma and chronic obstructive pulmonary disease.

Sponsor: University of North Carolina, Chapel Hill

You may qualify if…

  • Patients who have a high suspicion for the diagnosis of PCD, based on clinical features
  • Healthy Volunteers who have a family member with confirmed PCD.

Where it's recruiting

North Carolina

Chapel Hill

Source: ClinicalTrials.gov · NCT00807482 · last updated 2026-06-29

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease · TrialPath