RecruitingAlpha-1 Antitrypsin DeficiencyAAT DeficiencyAATD
Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to look at how Alpha-1-antitrypsin (AAT) deficiency and Cystic Fibrosis (CF) affect white blood cells in the lungs, called macrophages, and their ability to work.
Sponsor: University of Florida
You may qualify if…
- ✓ Signed informed consent
- ✓ Male or female 18 years of age or older
- ✓ Negative pregnancy test for women of childbearing potential
- ✓ Hemoglobin \>12.5 g/dl measured on the day of participation
- ✓ Negative urine nicotine test
You may not qualify if…
- ✕ Pregnancy or breastfeeding
- ✕ Weight \< 50 kg
- ✕ History of anemia requiring blood transfusions, erythropoietin supplementation, or iron supplementation within the past 36 months
- ✕ Known hemoglobin \<12.5 g/dl within the past 90 days
- ✕ Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \>100 mmHg
- ✕ Poor venous access
- ✕ Large volume blood donation (\>200 ml or 7 ounces) within the previous 56 days (e.g. blood donation for the purposes of blood banking)
- ✕ Clinically significant cardiac, hemostatic or neurological impairment or any other significant medical condition that, in the opinion of the investigator would affect subject safety (e.g., recent myocardial infarction, history of prolonged bleeding time, cerebral vascular accident, advanced cancer or uncontrolled medical condition)
Where it's recruiting
Florida
Gainesville
Source: ClinicalTrials.gov · NCT01851642 · last updated 2025-11-06