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RecruitingStrokeHemiparesis

Human-Machine System for the H2 Lower Limb Exoskeleton

Eligible age

18–75 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

This research study will investigate the use of smart lower limb robotic exoskeleton (developed by the CSIC, Spain) in rehabilitation after stroke. It will compare robotic-assisted rehabilitation with supervised motor practice. Additionally, it will also examine the use of noninvasive scalp electroencephalography (EEG) to learn specific brain wave patterns associated with learning to walk on the powered lower limb exoskeleton. The findings will be used to understand human-robot interaction and to design smart orthotic devices that can be controlled by thought activity and assist those that have lost all or part of their walking abilities.

Sponsor: University of Houston

You may qualify if…

  • Sub-acute or chronic stroke i.e., interval of at least 3 months or interval of at least 6 months from stroke to time of enrollment, respectively;
  • Cognitive ability to assimilate and participate actively in the treatment protocol (Mini Mental State Examination score \> 24 points, out of a total 30 indicating normal cognitive ability);
  • Modified Rankin scale scores 2-4 (Mild-Moderate functional disability post-stroke);
  • Modified Ashworth Scale of Spasticity score \<= 2 (ranges from 0-4 with 4 reflecting maximum spasticity);
  • Have no skin integrity issues;
  • Sufficient passive range of motion at the hip (at least 90 deg flexion, 15-20 deg extension), knee (90 deg flexion, complete extension) and ankle (15 deg dorsiflexion, 15 deg plantarflexion);
  • Have no contraindications to standing or walking; able to stand with assistive device for at least 5 minutes, and able to walk with assistive device for 10 m.
  • Able to understand and sign the consent form

You may not qualify if…

  • Severe cognitive and/or visual deficit;
  • Hemineglect (determined based on medical record or initial clinical assessment);
  • Severe sensory deficit;
  • Joint contractures of any extremity that limits normal range of motion during ambulation with assistive devices;
  • Skin lesions that may hinder or prevent the application of exoskeleton;
  • Uncontrolled angina;
  • Severe chronic obstructive pulmonary disease;
  • Other medical contraindications; any medical co-morbidities that would prevent standard rehabilitation.

Where it's recruiting

Texas

Houston

Source: ClinicalTrials.gov · NCT02114450 · last updated 2024-10-30

Human-Machine System for the H2 Lower Limb Exoskeleton · TrialPath