Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
Eligible age
18–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life. A second purpose is to find out what causes PTSD patients to have high adrenaline levels during stress. This study will also test if a medicine called losartan improves high adrenaline levels in patients with PTSD and if a certain gene that has to do with high blood pressure might be associated with high adrenaline levels.
Sponsor: Emory University
You may qualify if…
- ✓ veterans ages 18-65 years old with PTSD and without PTSD (controls) matched for age, gender, and race.
You may not qualify if…
- ✕ pregnancy
- ✕ hypertension
- ✕ diabetes
- ✕ heart or vascular disease
- ✕ illicit drug use
- ✕ excessive alcohol use (\>2 drinks per day)
- ✕ hyperlipidemia
- ✕ autonomic dysfunction
Where it's recruiting
Decatur
Source: ClinicalTrials.gov · NCT02560805 · last updated 2026-05-18