RecruitingMultiple SclerosisParkinson DiseaseAmyotrophic Lateral Sclerosis
Biomarkers of Synaptic Damage in Multiple Sclerosis
Eligible age
18–65 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
A prospective and retrospective cohort study of about five years will be performed on blood and cerebrospinal fluid samples taken for diagnostic reasons from recruited patients within the Neuromed Neurology Unit. Subjects with other chronic neurodegenerative diseases such as Amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD), and healthy subjects subjected to blood sampling and / or lumbar puncture for clinical reasons will be recruited As control groups.
Sponsor: Neuromed IRCCS
You may qualify if…
- ✓ 1. Male and female patients (age between 18 and 65 years)
- ✓ 2. Diagnosis of MS in accordance with McDonald's (2010 rev) criteria,
- ✓ 3. EDSS between 0 and 5.5 (included),
- ✓ 4. Patients able to provide informed consent to participation in the study
You may not qualify if…
- ✕ 1. Inability to provide informed written consent
- ✕ 2. Altered basal blood count
- ✕ 3. Pregnancy or lactation
- ✕ 4. Contraindications for the execution of magnetic resonance imaging with gadolinium
- ✕ 5. Significant clinical conditions in addition to SM or other chronic neurodegenerative diseases including latent viral infections
Source: ClinicalTrials.gov · NCT03217396 · last updated 2022-10-28