RecruitingPersistent Atrial FibrillationLongstanding Persistent Atrial Fibrillation

Medtronic Terminate AF Study

Eligible age

18+ yrs

Accepts

All genders

Locations

11 states

Healthy volunteers

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About this study

The purpose of this study is to demonstrate the safety and effectiveness of the Cardioblate iRF and CryoFlex hand held devices for the treatment of non-paroxysmal atrial fibrillation (AF).

Sponsor: Medtronic Cardiac Surgery

You may qualify if…

✓ History of non-paroxysmal AF (persistent or longstanding persistent)
✓ Concomitant indication for non-emergent open-heart surgery, eg,
✓ 1. Coronary artery bypass grafting
✓ 2. Valve repair or replacement
✓ Able to take the anticoagulant warfarin or novel oral anticoagulants (NOAC)

You may not qualify if…

✕ Wolff-Parkinson-White syndrome
✕ New York Heart Association (NYHA) Class = IV
✕ Left Ventricular Ejection Fraction ≤ 30%
✕ Need for emergent cardiac surgery (ie, cardiogenic shock) or redo open heart surgery
✕ Previous AF ablation, atrioventricular (AV) -nodal ablation, or surgical Maze procedure
✕ Contraindication for anticoagulation therapy
✕ Left atrial diameter \> 6.0 cm
✕ Preoperative need for an intra-aortic balloon pump or intravenous inotropes