RecruitingKidney Failure, ChronicHyperphosphatemia
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
During end-stage kidney disease, clinical guidelines suggest reducing elevated phosphate levels in the blood. However, the effect of lowering blood phosphate levels on important patient-centred outcomes has never been tested. This trial will evaluate whether compared to high levels, lowering blood phosphate levels would reduce death or major events due to heart disease, improve physical health, and be cost-effective.
Sponsor: The University of Queensland
You may qualify if…
- ✓ 1. Age ≥45 years, or Age ≥18 years with diabetes,
- ✓ 2. ESKD on haemodialysis or peritoneal dialysis, for at least 3 months,
- ✓ 3. Currently prescribed at least one phosphate-lowering medication at any dose
- ✓ 4. Able to provide informed consent
You may not qualify if…
- ✕ 1. Elective kidney transplantation scheduled,
- ✕ 2. Concomitant major illness / comorbidity that may result in death in the next 6 months in the view of the treating physician,
- ✕ 3. Participation in an interventional study that is likely to affect serum phosphate concentration.
Where it's recruiting
Washington
Armadale
Source: ClinicalTrials.gov · NCT03573089 · last updated 2026-08-26