RecruitingHerpes Zoster
A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant
Eligible age
1–17 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this study is to evaluate the reactogenicity, safety and immunogenicity of 2 doses of PED-HZ/su, GSK's vaccine candidate for the prevention of Herpes Zoster (HZ) in immunocompromised paediatric renal transplant recipients aged 1-17 years
Sponsor: GlaxoSmithKline
You may qualify if…
- ✓ Subjects' parent(s)/Legally Acceptable Representative(s) \[LAR(s) who, in the opinion of the investigator, can and will comply, with the requirements of the protocol
- ✓ Written or witnessed/thumb printed informed consent obtained from the parent(s)/LAR(s) of the subject prior to performance of any study specific procedure.
- ✓ Written informed assent obtained from the subjects when applicable according to local requirements.
- ✓ A male or female between, and including, 1 and 17 years of age at the time of randomisation (Visit Day 1)
- ✓ Body weight ≥ 6 kg/13.23 pounds.
- ✓ A subject is eligible if they meet at least one of the following criteria:
- ✓ Documented previous VZV vaccination OR
- ✓ Medically verified varicella (with source documentation) OR
You may not qualify if…
- ✕ Medical conditions
- ✕ Any primary kidney disease with a high incidence of recurrent primary kidney disease within the allograft
- ✕ Evidence of recurrent primary kidney disease within the current allograft
- ✕ Previous allograft loss secondary to recurrent primary kidney disease
- ✕ History of more than one organ transplanted (that is, kidney-liver, simultaneous double kidney or kidney-other organ(s) transplanted).
- ✕ Subjects with an episode of acute allograft rejection over the six months (180 days) prior to enrolment
- ✕ Panel Reactive Antibodies (PRA) calculated PRA (cPRA) or Calculated Reaction Frequency (cRF) score that is unknown at the time of transplant
- ✕ VZV serostatus unknown prior to transplant
Source: ClinicalTrials.gov · NCT04006808 · last updated 2026-02-27