RecruitingParkinson Disease
Globus Pallidus Stimulation to Treat Insomnia
Eligible age
40–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
Researchers are to determine if turning on an additional unilateral DBS (deep brain stimulation) electrode with stimulation to the globus pallidus externa (GPe) region of the brain will improve insomnia (sleep).
Sponsor: Mayo Clinic
You may qualify if…
- ✓ 40-80 years of age
- ✓ Symptomatic with Parkinsonism for 7-20 years
- ✓ Severe insomnia based on ISI score
You may not qualify if…
- ✕ Clinically significant dementia (MMSE \<23)
- ✕ Hoehn \& Yahr \[Hoehn, 1967 #1839\] stage I or V disease
- ✕ Other significant neurological or psychiatric disease
- ✕ Previous pallidotomy or thalamotomy
- ✕ Previous placement of other implantable devices
- ✕ Secondary parkinsonism (non-idiopathic parkinsonism)
- ✕ Inability to travel to Jacksonville for post-operative study visits
- ✕ Severe sleep apnea
Where it's recruiting
Florida
Jacksonville
Source: ClinicalTrials.gov · NCT04116996 · last updated 2025-12-01