RecruitingMalignant Neoplasm

Molecular Genetics Studies of Cancer Patients and Their Relatives

Eligible age

All ages

Accepts

All genders

Locations

17 states

Healthy volunteers

Yes

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About this study

This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.

Sponsor: City of Hope Medical Center

You may qualify if…

✓ Individuals must have a personal history of cancer and/or a family history of cancer suggestive of the presence of an inherited predisposition. This inherited predisposition might manifest as:
✓ Young age cancer diagnosis
✓ Multiple primary neoplasms in affected member
✓ The presence of rare tumor types in the family
✓ Congenital malformations
✓ Any other family clustering of cancer
✓ Any other cancer-predisposing genetic diseases/conditions
✓ Individuals may also be eligible by participation in the City of Hope Cancer Screening \& Prevention Program Network (CSPPN) clinical service or on the basis of membership in a group known or suspected to have an increased risk of carrying a genetic alteration or of sustaining a particular exposure that would place that at increased risk of cancer. (Examples would include members of occupational cohorts like asbestos workers, individuals with multiple dysplastic nevi in the absence of a family history of cancer, and individuals descended from a particular tribe in the American Southwest who have an increased incidence of a rare genetic alteration associated with an increased risk of a specific cancer.)

You may not qualify if…

✕ A family may be ineligible for study if the historian will not allow access to anyone within the family and thus, the accuracy of the family history cannot be established