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RecruitingPancreatic Neoplasm

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

Eligible age

50–75 yrs

Accepts

All genders

Locations

41 states

Healthy volunteers

No

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About this study

The purpose of this study is to compare two approaches for monitoring pancreatic cysts as well as to identify associated biomarkers. The study doctors want to compare more frequent monitoring versus less frequent monitoring as well as identify biomarkers which may improve risk detection of transformation to pancreatic cancer. The study doctors want to learn which monitoring method and which biomarkers lead to better outcomes for patients.

Sponsor: ECOG-ACRIN Cancer Research Group

You may qualify if…

  • Patient must be ≥ 50 years and ≤ 75 years of age
  • Patient must not have acute pancreatitis or a history of chronic pancreatitis
  • Patient must have received a CT, MRI, or EUS within 6 months prior to enrollment that revealed one or more ≥ 1 cm pancreatic cyst(s).
  • Patients of childbearing potential must not be known to be pregnant
  • Patient must not have a prior diagnosis of pancreatic malignancy of any type
  • Patient must not have a history of pancreatic resection
  • Patients with only pancreatic lesions without malignant risk (pancreatic pseudocyst or classic serous cystic lesion) are not eligible
  • Patient must not have a family history of pancreatic adenocarcinoma in one or more first-degree relatives (biological parents, full siblings or children)

Where it's recruiting

Alabama

Birmingham · Mobile

Alaska

Anchorage

Arizona

Phoenix · Scottsdale

Arkansas

Little Rock

California

Burbank · Encinitas · La Jolla · Loma Linda

Connecticut

Derby · Fairfield · Glastonbury · Greenwich

Delaware

Lewes · Millville · Newark · Rehoboth Beach

District of Columbia

Washington D.C.

Florida

Fort Lauderdale · Fort Myers · Jacksonville

Georgia

Atlanta

Idaho

Boise · Caldwell · Fruitland · Meridian

Illinois

Aurora · Barrington · Bloomington · Canton

Source: ClinicalTrials.gov · NCT04239573 · last updated 2026-06-17