Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
Eligible age
50–75 yrs
Accepts
All genders
Locations
41 states
Healthy volunteers
No
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About this study
The purpose of this study is to compare two approaches for monitoring pancreatic cysts as well as to identify associated biomarkers. The study doctors want to compare more frequent monitoring versus less frequent monitoring as well as identify biomarkers which may improve risk detection of transformation to pancreatic cancer. The study doctors want to learn which monitoring method and which biomarkers lead to better outcomes for patients.
Sponsor: ECOG-ACRIN Cancer Research Group
You may qualify if…
- ✓ Patient must be ≥ 50 years and ≤ 75 years of age
- ✓ Patient must not have acute pancreatitis or a history of chronic pancreatitis
- ✓ Patient must have received a CT, MRI, or EUS within 6 months prior to enrollment that revealed one or more ≥ 1 cm pancreatic cyst(s).
- ✓ Patients of childbearing potential must not be known to be pregnant
- ✓ Patient must not have a prior diagnosis of pancreatic malignancy of any type
- ✓ Patient must not have a history of pancreatic resection
- ✓ Patients with only pancreatic lesions without malignant risk (pancreatic pseudocyst or classic serous cystic lesion) are not eligible
- ✓ Patient must not have a family history of pancreatic adenocarcinoma in one or more first-degree relatives (biological parents, full siblings or children)
Where it's recruiting
Birmingham · Mobile
Anchorage
Phoenix · Scottsdale
Little Rock
Burbank · Encinitas · La Jolla · Loma Linda …
Derby · Fairfield · Glastonbury · Greenwich …
Lewes · Millville · Newark · Rehoboth Beach …
Washington D.C.
Fort Lauderdale · Fort Myers · Jacksonville
Atlanta
Boise · Caldwell · Fruitland · Meridian …
Aurora · Barrington · Bloomington · Canton …
Source: ClinicalTrials.gov · NCT04239573 · last updated 2026-06-17