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RecruitingHemorrhoids

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

Eligible age

18–100 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.

Sponsor: University of Oklahoma

You may qualify if…

  • Adults aged 18-100
  • Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids.

You may not qualify if…

  • Inability to undergo general anesthesia
  • Contraindications to hemorrhoidectomy
  • History of schizophrenia or other hallucinatory psychiatric illnesses
  • History of psychosis
  • Chronic narcotic usage defined as either having a pain contract with a pain management specialist and no narcotic usage for one month prior to hemorrhoidectomy.

Where it's recruiting

Oklahoma

Oklahoma City

Source: ClinicalTrials.gov · NCT04248205 · last updated 2026-04-01