RecruitingStroke
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Eligible age
21–100 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.
Sponsor: Northwestern University
You may qualify if…
- ✓ Age at enrollment is 21 or older
- ✓ Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening
- ✓ Severe to moderate motor impairment (FMA-UE of 7-40)
- ✓ At least some voluntary shoulder and elbow muscle activation
You may not qualify if…
- ✕ Inability to follow instructions of the MyoCI task
- ✕ Visual impairment (such as hemianopia) preventing full view of screen
- ✕ Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest)
- ✕ Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
- ✕ Inability to understand or follow commands in English due to aphasia or other reason
- ✕ Diffuse or multifocal infarcts in both hemispheres
- ✕ Substantial arm pain preventing participation for 90 minutes a day
- ✕ Spasticity treatment (pharmacological or Botox) within last 3 months
Where it's recruiting
Illinois
Chicago
Source: ClinicalTrials.gov · NCT04312269 · last updated 2026-05-27