RecruitingAdipose Tissue, BrownAdipose TissueObesity
The Physiology of Human Brown Adipose Tissue
Eligible age
18–75 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Brown fat is a type of fat, found in both children and adults, which can produce heat and regulate the body's metabolism and energy use. White fat is the more common type of fat which is used to store extra calories. Understanding more about differences between brown and white fat may allow us to develop new approaches to improve the body's metabolism.
Sponsor: Beth Israel Deaconess Medical Center
You may qualify if…
- ✓ 1\. Healthy participants between age 18 and 75 years undergoing planned clinically indicated procedure at BIDMC.
You may not qualify if…
- ✕ 1. Body mass index (BMI) greater than or equal to 40 kg/m2
- ✕ 2. History of any local or systemic infectious disease with fever or requiring antibiotic within four weeks of drug administration;
- ✕ 3. Diabetes, either previously diagnosed or hemoglobin A1c greater than or equal to 6.5%
- ✕ 4. Use of oral or parenteral corticosteroids (epidural permitted) or other medication known to cause insulin resistance in the previous 6 weeks.
- ✕ 5. Willingness to provide informed consent and follow study procedures, including attending scheduled visits.
- ✕ 6. Chronic kidney disease stage 4 or 5 (including end-stage renal disease);
- ✕ 7. Hepatic disease, including serum alanine aminotransferase (ALT) or aspartate transaminase (AST) greater than or equal to 3 times the upper limit of normal; hepatic synthetic insufficiency as defined as serum albumin \< 3.0 g/dL; or serum bilirubin \> 2.0;
- ✕ 8. Active malignancy (except squamous or basal cell carcinoma of skin)
Where it's recruiting
Massachusetts
Boston
Source: ClinicalTrials.gov · NCT04352244 · last updated 2025-10-31