RecruitingSpinal Cord Injuries
Effects of 5HTP on the Injured Human Spinal Cord
Eligible age
18–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
This study will assess how the serotonin precursor, 5-HTP, alter nervous system excitability and motor function in individuals with spinal cord injuries of differing chronicity and severity. Participants will visit the lab on 4 separate occasions where they will be administered four different drugs in a randomized, double-blinded, placebo-controlled crossover design.
Sponsor: University of Alberta
You may qualify if…
- ✓ participants must have suffered trauma to the spinal cord at least six months ago or longer
You may not qualify if…
- ✕ individuals with damage to the nervous system other than to the spinal cord
- ✕ pregnant and/or breastfeeding women
- ✕ alcoholic participants
- ✕ history of seizure/epilepsy
- ✕ history of suicidal thoughts or behaviors
- ✕ known or suspected allergy to the medication ingredients
- ✕ cardiovascular disease including history of heart attack or heart rhythm irregularities
- ✕ coronary artery disease
Where it's recruiting
Kentucky
Louisville
Source: ClinicalTrials.gov · NCT04520178 · last updated 2025-08-27