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Jump: MR Simulation For Radiation Therapy Master Protocol

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This is a master protocol for a prospective Phase I-II study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatments.

Sponsor: Brigham and Women's Hospital

You may qualify if…

  • ✓ Participants must have a confirmed malignancy requiring radiation therapy.
  • ✓ Age: 18 years or older
  • ✓ ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
  • ✓ Ability to understand and the willingness to sign a written informed consent document.
  • ✓ Disease-specific eligibility criteria will be specified in the appropriate subprotocol.

You may not qualify if…

  • ✕ For MRI involving contrast, history of allergic reactions attributed to gadolinium based IV contrast. Note: If patient will not receive contrast, this is not applicable
  • ✕ Participants who cannot undergo an MRI
  • ✕ Disease-specific exclusion criteria will be specified in the appropriate subprotocol

Where it's recruiting

Source: ClinicalTrials.gov · NCT04545957 · last updated 2026-07-20

Jump: MR Simulation For Radiation Therapy Master Protocol · TrialPath