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RecruitingAsthmaCOPDInterstitial Lung Disease

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

Eligible age

3+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.

Sponsor: Mario Castro, MD, MPH

You may qualify if…

  • Healthy Volunteers:
  • Subject has no diagnosed pulmonary conditions
  • Ability to read and understand English or Spanish
  • Subjects with Lung Disease:
  • Subject has a diagnosis of pulmonary dysfunction made by a physician
  • No acute worsening of pulmonary function in the past 30 days
  • Ability to read and understand English or Spanish

You may not qualify if…

  • MRI is contraindicated based on responses to MRI screening questionnaire
  • Subject is pregnant or lactating
  • Subject does not fit into 129Xe vest coil used for MRI
  • Subject cannot hold his/her breath for 15-16 seconds
  • Subject deemed unlikely to be able to comply with instructions during imaging
  • Oxygen saturation \<88% on room air or with supplemental oxygen
  • Cognitive deficits that preclude ability to provide consent
  • Institutionalization

Where it's recruiting

Kansas

Kansas City

Source: ClinicalTrials.gov · NCT04624490 · last updated 2026-05-06