RecruitingPrimary Sclerosing CholangitisPSCCholangiocarcinoma
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
Eligible age
18–85 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
The purpose of this research is to create a collection of bile, bile duct brushings and medical information from people with Primary Sclerosing Cholangitis (PSC) and controls to learn more about changes that occur in the liver.
Sponsor: Mayo Clinic
You may qualify if…
- ✓ PSC
- ✓ Patients diagnosed with PSC between the age of 18 and 85.
- ✓ The diagnosis of PSC will be based on standard PSC criteria including clinical and biochemical evidence of chronic cholestasis of at least six months duration, positive cholangiographic findings and compatible liver biopsies if available.
- ✓ Women with PSC of childbearing potential and pregnant women will be offered enrollment because there is no risk to an unborn child in this investigation. Patients with PSC and Cholangiocarcinoma will be included.
- ✓ Controls
- ✓ Controls without history of PSC or evidence of other chronic liver disease of either gender that will participate in this study should be between the ages of 18-85.
You may not qualify if…
- ✕ Patients unable to provide inform consent.
- ✕ Prisoners and institutionalized individuals.
- ✕ PSC with orthotopic liver transplantation
- ✕ History of Roux En Y procedure
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT04753996 · last updated 2026-02-17