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RecruitingDisorderHeartPostoperative

Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery

Eligible age

18–65 yrs

Accepts

All genders

Locations

4 states

Healthy volunteers

No

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About this study

TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.

Sponsor: Unity Health Toronto

You may qualify if…

  • 1. ≥18 and ≤65 years of age
  • 2. Planned cardiac surgery using cardiopulmonary bypass
  • 3. Informed consent obtained
  • 4. Preoperative European System for Cardiac Operative Risk Evaluation (EuroSCORE I) of 6 or more

You may not qualify if…

  • 1. Patients who refuse participation
  • 2. Patients who are unable to receive or who refuse blood products
  • 3. Patients who are involved in a preoperative autologous pre-donation program
  • 4. Patients who are having a heart transplant or having surgery solely for an insertion of a ventricular assist device
  • 5. Pregnancy or lactation (a negative pregnancy test must be obtained prior to randomization for women of childbearing potential)

Where it's recruiting

Maine

Portland

New York

New York

Pennsylvania

Philadelphia

Source: ClinicalTrials.gov · NCT04754022 · last updated 2024-11-21