RecruitingGestational DiabetesPregnancy, High RiskOverweight and Obesity
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Eligible age
18–45 yrs
Accepts
Women
Locations
5 states
Healthy volunteers
No
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About this study
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Sponsor: Indiana University
You may qualify if…
- ✓ Pregnant women between the ages of 18-45
- ✓ Singleton gestation
- ✓ Gestational age between 12 0/7-32 6/7 weeks' gestation with gestational diabetes diagnosed during this time frame using either a 50g 1-hr GCT ≥200 mg/dL or two or more abnormal values on a 100g OGTT using the Carpenter-Coustan Criteria
- ✓ Overweight or obese BMI at the first prenatal visit (BMI ≥25 kg/m2 or ≥23 kg/m2 in Asian Americans)
You may not qualify if…
- ✕ Inability or unwillingness to provide informed consent
- ✕ Inability to communicate with members of the study team, despite the presence of an interpreter
- ✕ Planned delivery at a non-study affiliated hospital
- ✕ Known renal disease with a baseline creatinine \>1.5 mg/dL
- ✕ Significant fetal anomalies diagnosed prior to study enrollment (these will include anomalies such as gastroschisis, spina bifida, complex congenital heart disease, or serious karyotypic anomalies that may lead to early delivery or increased risk of neonatal death)
- ✕ Oral or IV/IM steroid use within 7 days of study enrollment
Where it's recruiting
Source: ClinicalTrials.gov · NCT05124808 · last updated 2026-06-24