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RecruitingType 1 Diabetes

Lipoprotein Kinetics in T1D

Eligible age

18–45 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this research study is to understand how type 1 diabetes (T1D) increases the risk for cardiovascular diseases (heart attack and stroke). To this end, the investigators will compare apolipoprotein and triglyceride kinetics in people wtih T1D and healthy control participants.

Sponsor: University of Missouri-Columbia

You may qualify if…

  • Age: ≥18 but ≤45 years
  • premenopausal/eumenorrheic and not pregnant or breastfeeding
  • non-obese (body mass index ≥18.5\<30.0 kg/m2)
  • Fasting plasma triglyceride \<150 mg/dL
  • Additional inclusion criteria for control subjects:
  • Fasting plasma glucose \<100 mg/dL
  • Plasma glucose 2 h after a 75 g oral glucose challenge \<140 mg/dL
  • HbA1c \<5.6%.

You may not qualify if…

  • more than 1.5 h of structured exercise/week
  • use of tobacco products, excessive amounts of alcohol, or dietary supplements and/or medications known to affect lipid metabolism
  • hypothyroidism or other disorders known to affect lipid metabolism
  • conditions that would make it impossible to complete the study protocol

Where it's recruiting

Missouri

Columbia

Source: ClinicalTrials.gov · NCT05179954 · last updated 2026-02-10