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RecruitingCirrhosisEnd Stage Liver DIseaseLiver Cirrhosis

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.

Sponsor: Massachusetts General Hospital

You may qualify if…

  • 1. Adult patients ≥ 18 years old with diagnosis of cirrhosis based on histology, radiology, and/or elastography presenting to the emergency department or inpatient general medicine service
  • 2. Patients must have one of the following:
  • 1. Ascites (requiring diuretics or serial large volume paracenteses)
  • 2. Hepatic hydrothorax (requiring diuretics)
  • 3. Hepatic encephalopathy (requiring medications)

You may not qualify if…

  • 1. History of solid organ transplantation
  • 2. On hemodialysis
  • 3. MELD score \> 20
  • 4. Score \<10 on Simplified Animal Naming Test (S-ANT1)
  • 5. Current admission for hemodynamically significant GI bleeding or alcohol withdrawal
  • 6. Require routine administration of controlled substances
  • 7. Those deemed ineligible based on the MGH Home Hospital, inpatient medicine or hepatology clinician evaluation

Where it's recruiting

Source: ClinicalTrials.gov · NCT05205954 · last updated 2025-07-24

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention · TrialPath