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RecruitingRelapsed Adult AMLPrimary Refractory Acute Myeloid LeukemiaHigh Risk Acute Myeloid Leukemia

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Eligible age

18–120 yrs

Accepts

All genders

Locations

17 states

Healthy volunteers

Yes

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About this study

This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).

Sponsor: Massachusetts General Hospital

You may qualify if…

  • Patient Inclusion Criteria
  • Hospitalized patients (age ≥ 18 years) with high-risk AML defined as:
  • Patients with new diagnosis ≥ 60 years of age
  • An antecedent hematologic disorder
  • Therapy related-disease
  • Relapsed or primary refractory AML
  • Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial.
  • Caregiver Inclusion Criteria

You may not qualify if…

  • \- Patient Exclusion Criteria
  • Patients with a diagnosis of acute promyelocytic leukemia (APML)
  • Patients with AML receiving supportive care alone
  • Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits informed consent or compliance with study procedures
  • Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment
  • Patients expected to be discharged within 2 days

Where it's recruiting

Alabama

Birmingham

California

Stanford

Colorado

Denver

Florida

Miami · Tampa

Georgia

Atlanta

Illinois

Evanston

Indiana

Bloomington

Maryland

Baltimore

Minnesota

Rochester

New York

Rochester

North Carolina

Chapel Hill · Durham

Source: ClinicalTrials.gov · NCT05237258 · last updated 2025-07-25