Time Restricted Eating During Chemotherapy for Breast Cancer
Eligible age
25–99 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Breast cancer is the most common cancer in the United States however, little is known about how diet can affect cancer treatment. Pre-clinical murine studies report intermittent fasting increases effectiveness of chemotherapy and decreases treatment related adverse events. The proposed research will demonstrate that time restricted eating, a form of intermittent fasting, will improve treatment related outcomes, patient related outcomes, and limit treatment related weight gain and fat mass accretion.Time restricted eating combined with a mediterranean diet will also be feasible and improve cardiometabolic risk more than TRE alone or standard care.
Sponsor: University of Illinois at Chicago
You may qualify if…
- ✓ Age 25-99 at time of consent
- ✓ ECOG 0 or 1
- ✓ Breast cancer to meet histologically confirmed Stage I-III.
- ✓ Demonstrates adequate organ function (absolutely neutrophil count ≥ 1,500/μL).
- ✓ All screening labs to be obtained within 30 days prior to registration.
- ✓ Able to provide written informed consent and HIPAA authorization for release of personal health information, via an approved UIC Institutional Review Board (IRB) informed consent form and HIPAA authorization.
- ✓ Women of childbearing potential must not be pregnant or breast-feeding. A negative serum or urine pregnancy test is required per institutional practice guidelines.
- ✓ As determined at the discretion of the enrolling physician or protocol designee, ability of the subject to understand and comply with study procedures for the entire length of the study.
You may not qualify if…
- ✕ Women with metastatic disease or type 1 or 2 diabetes
- ✕ Women with BMI ≥ 40kg/m2 and \< 25kg/m2
- ✕ Women who are pregnant. A negative serum or urine pregnancy test is required per institutional practice guidelines.
- ✕ Night shift workers
- ✕ Women with a history of eating disorders
- ✕ Enrolled participants with a significant weight loss or weight gain within 3 months of the study (weight gain or loss \>4kg)
- ✕ Active infection requiring systemic therapy
- ✕ Uncontrolled HIV/AIDS or active viral hepatitis
Where it's recruiting
Chicago
Source: ClinicalTrials.gov · NCT05259410 · last updated 2025-10-01