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RecruitingPostpartum PreeclampsiaHypertension in Pregnancy

Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial

Eligible age

19+ yrs

Accepts

Women

Locations

1 state

Healthy volunteers

No

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About this study

Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.

Sponsor: Nebraska Methodist Health System

You may qualify if…

  • Any patient admitted for delivery by cesarean or vaginal delivery at 24 weeks gestation or greater with hypertension(HTN). Hypertension will be defined during the study as either a systolic blood pressure ≥140mmHg or diastolic blood pressure ≥90mmHg on two occasions at least 4 hours apart. This definition is consistent with the ACOG definition for pregnancy related HTN. Following enrollment, treatment will be escalated at discretion of primary provider with the goal of normotension.

You may not qualify if…

  • History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema
  • Contraindication to either Nifedipine or Labetalol
  • HR \<60 or \>110
  • Native language other than English or Spanish

Where it's recruiting

Source: ClinicalTrials.gov · NCT05309460 · last updated 2024-04-12