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RecruitingObesity

Predictors of Behavioral Obesity Treatment Outcomes

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown. This project will characterize the mechanisms through which adverse daily experiences and present bias -- a cognitive adaptation to harsh and unpredictable environments -- account for disparities in weight loss outcomes.

Sponsor: Rush University Medical Center

You may qualify if…

  • 1. Age ≥18 years old
  • 2. Obesity (body mass index ≥30 kg/m2)
  • 3. Meets criteria for either the lower SES or higher SES cohort

You may not qualify if…

  • 1. Not fluent in English
  • 2. Change in income or financial assets exceeding ±75% of federal poverty guideline within the past 12 months, or expected in the next 6 months, if this change would result in reclassification on SES.
  • 3. Previous or planned bariatric surgery, or concurrent engagement in other behavioral or pharmacological treatment for obesity
  • 4. Resides more than 20 miles away from Rush, or planning to move outside of this geographic area during the study period
  • 5. Body mass index ≥60 kg/m2, due to increased injury risk with exercise
  • 6. History of bariatric surgery, or current engagement in another weight loss therapy
  • 7. Lack of reliable access to cell or landline phone
  • 8. Medical contraindications to treatment, including osteoporosis, cognitive impairment (Montreal Cognitive Assessment ≤25), active substance abuse based on the World Health Organization's ASSIST screener, lack of physician clearance for participation, or serious medical illness (e.g., stage 3 or 4 heart failure, cancer, renal failure, etc.)

Where it's recruiting

Illinois

Chicago

Source: ClinicalTrials.gov · NCT05326477 · last updated 2026-03-11

Predictors of Behavioral Obesity Treatment Outcomes · TrialPath