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RecruitingAtrial FibrillationArrhythmias, Cardiac

Machine Learning in Atrial Fibrillation

Eligible age

22–80 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

Atrial fibrillation is a serious public health issue that affects over 5 million Americans (Miyazaka, Circulation 2006) in whom it may cause skipped beats, dizziness, stroke and even death. Therapy for AF is currently suboptimal, in part because AF represents several disease states of which few have been delineated or used to successfully guide management. This study seeks to clarify this delineation of AF types using machine learning (ML).

Sponsor: Stanford University

You may qualify if…

  • undergoing ablation at Stanford of (a) paroxysmal AF (self-terminates \< 7 days), or (b) persistent AF (requires cardioversion to terminate).
  • Per our clinical practice and guidelines (Calkins et al, Heart Rhythm 2012), patients will have failed or be intolerant of ≥ 1 anti-arrhythmic drug.

You may not qualify if…

  • active coronary ischemia or decompensated heart failure
  • atrial or ventricular clot on trans-esophageal echocardiography
  • pregnancy (to minimize fluoroscopic exposure)
  • inability or unwillingness to provide informed consent
  • rheumatic valve disease (results in a unique AF phenotype)
  • thrombotic disease or venous filters

Where it's recruiting

California

Stanford

Source: ClinicalTrials.gov · NCT05371405 · last updated 2025-11-14