RecruitingNewly Diagnosed Glioblastoma
Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Proposed treatment of subjects with newly diagnosed glioblastoma with novel personalized drug regimens identified to be effective in vitro using cancer stem cells derived from their individual tumors, alongside standard of care radiation and TMZ.
Sponsor: Swedish Medical Center
You may qualify if…
- ✓ Histological diagnosis of GBM (WHO grade 4)
- ✓ Subjects ≥18 years of age
- ✓ Patients must have a life expectancy of \>6 months
- ✓ Patients must have a surgically accessible tumor with the intent for a gross or near total resection of the tumor mass (GBM, WHO grade 4)
- ✓ Patients must have a KPS rating of ≥70
- ✓ Patients should not have received any prior systemic anti-cancer therapy
- ✓ Patients must be negative for HIV, Hepatitis B and C
- ✓ Baseline hematologic studies and chemistry and coagulation profiles must meet the following criteria:
You may not qualify if…
- ✕ Metastatic disease
- ✕ Diseases or conditions that obscure toxicity or dangerously alter drug metabolism
- ✕ Serious intercurrent medical illness
- ✕ Inadequately controlled hypertension
- ✕ History of myocardial infarction or unstable angina within 6 months
- ✕ History of stroke or transient ischemic attack within 6 months
Where it's recruiting
Washington
Seattle
Source: ClinicalTrials.gov · NCT05380349 · last updated 2025-05-16