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RecruitingPainInflammatory Response

Association Between Body Composition and Pain in Spinal Cord Injury

Eligible age

18–70 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and explore the influence of body composition on these responses, in individuals with chronic spinal cord injury

Sponsor: University of Miami

You may qualify if…

  • Age 18-70 years
  • Spinal cord injury occurring at least 2 years prior to study entry
  • Neurological level of injury (LOI) between C4 and L2
  • American Spinal Injury Association Impairment Scale (AIS) A-D
  • English-speaking.

You may not qualify if…

  • Cognitive dysfunction that limits ability to adequately understand the risks of the study or are otherwise unable to consent
  • Health conditions associated with chronic systemic inflammation unrelated to weight or adiposity (e.g., systemic autoimmune diseases, recurrent or active urinary tract infection, pressure injury \> Stage 2)
  • Conditions that preclude measurement of body composition by dual-energy x-ray absorptiometry (DXA; e.g., lower limb contracture \> 15 degrees)
  • Inability to obtain free-flowing blood from a superficial forearm or hand vein
  • Pregnant women
  • Prisoners

Where it's recruiting

Florida

Coral Gables

Source: ClinicalTrials.gov · NCT05459207 · last updated 2026-03-19

Association Between Body Composition and Pain in Spinal Cord Injury · TrialPath