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RecruitingIron Deficiency AnemiaPregnancy

Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy

Eligible age

18–45 yrs

Accepts

Women

Locations

7 states

Healthy volunteers

No

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About this study

Double blind, placebo controlled, multicenter randomized trial in pregnant women in the U.S. (N=300) to test the central hypothesis that IV iron in pregnant women with IDA (Hb\<11 g/dL and ferritin\<30 ng/mL) at 13 - 30 weeks will be effective, safe and cost-effective in reducing severe maternal morbidity-as measured by maternal anemia at delivery-and will also improve offspring neurodevelopment.

Sponsor: Women and Infants Hospital of Rhode Island

You may qualify if…

  • Pregnant women between the ages of 18-45
  • Singleton gestation
  • Iron-deficiency anemia (serum ferritin \<30ng/mL and Hb\<11 g/dL)
  • At 13-30 weeks gestation
  • Plan to deliver at participating hospital

You may not qualify if…

  • Non-iron-deficiency anemia e.g thalassemia, sickle cell disease, B12 or folate deficiency, hypersplenism.
  • Malabsorptive syndrome, inflammatory bowel disease, gastric bypass, or sensitivity to oral or IV iron
  • Multiple gestation
  • Inability or unwillingness to provide informed consent
  • Inability to communicate with members of the study team, despite the presence of an interpreter
  • Planned delivery at a non-study affiliated hospital

Where it's recruiting

Alabama

Birmingham

Florida

Miami

Michigan

Ann Arbor

Missouri

St Louis

Oregon

Portland

Rhode Island

Providence

Utah

Salt Lake City

Source: ClinicalTrials.gov · NCT05462704 · last updated 2025-06-10