RecruitingInfertility of Uterine Origin
Platelet Rich Plasma for Insufficient Endometrium
Eligible age
18–45 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
To determine the effectiveness of an intrauterine PRP infusion on endometrial thickness and in vitro fertilization (IVF) outcomes in a population of infertile women with a history of unresponsive thin endometrium.
Sponsor: Reproductive Medicine Associates of New Jersey
You may qualify if…
- ✓ Patients who have previously undergone at least 2 unsuccessful frozen embryo transfer cycles, defined as failure to achieve a sustained clinical pregnancy (visualization of intrauterine gestational sac on ultrasound or a cancelled embryo transfer cycle due to inadequate endometrial thickness
- ✓ Patients with a diagnosis of thin endometrial lining (less than or equal to 6 mm maximum thickness) during prior unsuccessful or canceled embryo transfer cycles.
You may not qualify if…
- ✕ Fewer than 2 prior unsuccessful or canceled frozen embryo transfer cycles.
- ✕ Most recent unsuccessful embryo transfer prior to January 1, 2017.
- ✕ Mullerian anomalies, excluding arcuate uterus
- ✕ Concurrent submucosal fibroids, unrepaired uterine defects or present indication for uterine surgery
- ✕ Communicating hydrosalpinx without plans for surgical correction prior to study enrollment.
- ✕ Failure of patient to agree to enrollment in study with written consent.
- ✕ Concurrent pregnancy
- ✕ Anticoagulation use for which plasma infusion is contraindicated
Where it's recruiting
New Jersey
Basking Ridge
Source: ClinicalTrials.gov · NCT05538338 · last updated 2026-06-03