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RecruitingInsulin ResistanceDepressionDepressive Disorder

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Eligible age

12–17 yrs

Accepts

Women

Locations

1 state

Healthy volunteers

Yes

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About this study

The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.

Sponsor: Colorado State University

You may qualify if…

  • Female
  • Age 12-17 years
  • Body Mass Index (BMI)\>= 85 for age and sex
  • Type 2 Diabetes (T2D) first-or second-degree relative
  • Center for Epidemiologic Studies Depression Scale (CES-D) total score \>=21

You may not qualify if…

  • T2D/ Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training
  • Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse/ dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia/bulimia, \& schizophrenia
  • Insulin sensitizers, weight loss medications \& chronic steroids
  • Structured weight loss treatment or bariatric surgery
  • Pregnancy, nursing

Where it's recruiting

Colorado

Aurora · Fort Collins

Source: ClinicalTrials.gov · NCT05543083 · last updated 2026-04-22

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-R · TrialPath