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RecruitingIschemic Stroke

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.

Sponsor: Johns Hopkins University

You may qualify if…

  • Acute ischemic stroke demonstrated on an MRI scan that includes perfusion imaging with an exogenous contrast agent

You may not qualify if…

  • Inability to perform telephone-based cognitive assessments

Where it's recruiting

Maryland

Baltimore

Source: ClinicalTrials.gov · NCT05556395 · last updated 2025-09-29