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RecruitingLong-Term Memory DeclineMild Cognitive Impairment

Wayfinding Intervention and Long-Term Memory

Eligible age

60–85 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

Sponsor: University of California, San Francisco

You may qualify if…

  • fluent speakers of English
  • completed 12 or more years of education
  • normal or corrected-to-normal vision
  • dexterity to comfortably operate the scanner-compatible response box
  • freedom from physical and neurological conditions contra-indicated for fMRI
  • must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground

You may not qualify if…

  • use of psychotropic medications
  • history of concussions or dizziness, vestibular or balance problems
  • significant discomfort with virtual reality experiences

Where it's recruiting

California

San Francisco

Source: ClinicalTrials.gov · NCT05625425 · last updated 2026-05-07

Wayfinding Intervention and Long-Term Memory · TrialPath