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RecruitingPTSD

Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder

Eligible age

19–70 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

A double-blind randomized placebo-controlled trial to further investigate glecaprevir/pibrentasvir (GLE/PIB), a direct acting antiviral (DAA) that has been associated with posttraumatic stress disorder (PTSD) symptom improvement when prescribed for the treatment of chronic hepatitis C viral infection (HCV).

Sponsor: White River Junction Veterans Affairs Medical Center

You may qualify if…

  • 1. Age 19-70 years
  • 2. Weight ≥ 45 kg
  • 3. Diagnosed with PTSD as determined by the CAPS-5 within seven days of enrollment
  • 4. Eligible for Veterans Affairs healthcare
  • 5. If person with childbearing potential, use of acceptable method of birth control (i.e., effective contraceptives, abstinence) is required.
  • 6. Able to read, understand, and sign the informed consent document.
  • Exclusion (unable to participate) Criteria:
  • 1. Pregnant or lactating person

Where it's recruiting

Vermont

White River Junction

Source: ClinicalTrials.gov · NCT05637879 · last updated 2025-04-24

Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder · TrialPath