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RecruitingHepatocellular CarcinomaBiliary Tract Cancer

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

Eligible age

18+ yrs

Accepts

All genders

Locations

7 states

Healthy volunteers

No

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About this study

The purpose of this study is to assess the efficacy and safety of RP2 in combination with atezolizumab plus bevacizumab (Cohorts 1a and 1b) and RP2 monotherapy (Cohort 2) in the as second line treatment in patients with locally advanced unresectable, recurrent, and/or metastatic HCC and in combination with durvalumab as treatment in patients with unresectable locally advanced or metastatic BTC.

Sponsor: Replimune, Inc.

Where it's recruiting

California

Beverly Hills · La Jolla

Florida

Miami · Tampa

Maryland

Baltimore

New York

Buffalo · The Bronx

Pennsylvania

Philadelphia · Pittsburgh

Tennessee

Germantown · Knoxville

Texas

Houston

Source: ClinicalTrials.gov · NCT05733598 · last updated 2026-04-02