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RecruitingLiver Diseases

A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease

Eligible age

18+ yrs

Accepts

All genders

Locations

4 states

Healthy volunteers

No

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About this study

Patients with complications of advanced liver disease often have difficulties after hospital discharge that result in early hospital readmission. Poor outcomes for these patients during this transitional time could be improved through the use of innovative transitional care models. This proposal aims to examine the effect of a transitional care model, The Transitional Liver Clinic (TLC), in reducing hospital re-admissions, improving quality of life, and improving patient experience.

Sponsor: Indiana University

You may qualify if…

  • 1. Male or female age ≥18
  • 2. Diagnosis of advanced liver disease, defined as either (must meet either a or b)
  • 1. cirrhosis based on (either i or ii):
  • biopsy
  • characteristic clinical, laboratory, and imaging findings
  • 2. acute alcoholic hepatitis, defined by NIAAA Alcoholic Hepatitis Consortia, as
  • onset of jaundice (serum bilirubin \>3.0 mg/dL) in prior 8 weeks
  • consumption of \>40 (female) or 60 (male) g alcohol/day for ≥6 months, with \<60 days abstinence before jaundice onset,

You may not qualify if…

  • 1. discharge under hospice
  • 2. listed for liver transplant with MELD-Na ≥ 35
  • 3. unable or unwilling to participate in post-discharge follow-up either in-person or virtually
  • 4. unable to speak or understand English and/or Spanish
  • 5. low hearing or communicative ability (examiner rated) that would interfere with interventions and outcome assessments
  • 6. lack of access to a telephone
  • 7. incarcerated
  • 8. concurrent enrollment in an interventional research study

Where it's recruiting

Illinois

Chicago

Indiana

Indianapolis

Michigan

Ann Arbor

Pennsylvania

Philadelphia

Source: ClinicalTrials.gov · NCT05733832 · last updated 2025-10-24