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RecruitingObsessive-Compulsive Disorder

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The study assesses the safety and preliminary effectiveness of MDMA-assisted cognitive behavioral therapy in participants diagnosed with obsessive-compulsive disorder (OCD).

Sponsor: Carolyn Rodriguez

You may qualify if…

  • 1. At least 18 years old
  • 2. Fluent in speaking and reading the predominantly used or recognized language of the study site
  • 3. Able to swallow pills
  • 4. Meet the criteria for OCD diagnosis
  • 5. YBOCS total score of at least 16
  • 6. Not on psychotropic medications 1 month prior to study enrollment
  • 7. Able to tolerate a treatment-free period
  • 8. Able to tolerate study procedures

You may not qualify if…

  • 1. Pregnant or nursing, or able to become pregnant and are not practicing an effective means of birth control
  • 2. Weigh less than 48 kilograms (kgs)
  • 3. Any current problem which, in the opinion of the investigator or study physician, might interfere with participation

Where it's recruiting

California

Palo Alto

Source: ClinicalTrials.gov · NCT05783817 · last updated 2026-03-05