Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Eligible age
Up to 80 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older Veterans. Further, it will evaluate whether a weight loss intervention, including dietary modification and exercise, in obese Veterans with and without PCC will reduce systemic and adipose tissue inflammation and senescence and promote PCC recovery.
Sponsor: VA Office of Research and Development
You may qualify if…
- ✓ 1. U.S. Veteran
- ✓ 2. Self-reported COVID-19 naïve or COVID-19 \> 90 days ago for lean and obese PCC naïve or documented COVID-19 for the lean and obese PCC groups (At least one PCC symptom \>4 weeks)
- ✓ 3. Body Mass Index: 19-25 or 30-50 kg/m2
You may not qualify if…
- ✕ 1. Neurologic, musculoskeletal, or other condition that limits subject's ability to complete study physical assessments
- ✕ 2. Active inflammatory, COVID-19, autoimmune, infectious, hepatic (LFTs \> 2.5 x WNL), renal (eGFR\<45), gastrointestinal, malignant, and psychiatric disease
- ✕ 3. Uncontrolled diabetes (HbA1c \>10% or the current use of insulin)
- ✕ 4. Weight change within the past month of \>5 kg
- ✕ 5. Self-reported alcohol or drug abuse
- ✕ 6. Anti-coagulant medication usage
Where it's recruiting
Source: ClinicalTrials.gov · NCT05880108 · last updated 2026-06-01