RecruitingStrokeStroke, AcuteStroke, Ischemic

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

Eligible age

18+ yrs

Accepts

All genders

Locations

22 states

Healthy volunteers

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About this study

TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.

Sponsor: University of Cincinnati

You may qualify if…

✓ 1. Adult patients (≥18 years)
✓ 2. Moderate-to-severe pre-stroke functional disability, defined as mRS 3-4, for at least 3 months prior to stroke onset
✓ 3. Presenting to study hospital within 24 hours of last known well time
✓ 4. Diagnosis of acute ischemic stroke
✓ 5. Intracranial causative occlusion of the internal carotid artery or the M1 or dominant M2 segments of the middle cerebral artery visualized on the baseline CT(or MR) angiogram
✓ 6. Presenting CT Alberta Stroke Program Early CT (ASPECT) score ≥3 or MRI ASPECT score ≥4
✓ 7. Presenting NIH Stroke Scale score ≥6
✓ 8. Informed consent from patient if competent or from legally authorized representative

You may not qualify if…

✕ 1. Known diagnosis of a terminal cancer or terminal illness at the time of stroke
✕ 2. Assessment of pre-stroke functional status cannot be performed during the hospital stay
✕ 3. Pre-stroke disability deemed temporary in the investigator's opinion (for example, recovering from a general medical illness or traumatic bodily injury)