RecruitingAbdominal Wall Hernia
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
Eligible age
18+ yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction. The main question is will abdominal wall specific quality of life (using the HerQLes survey) for the group undergoing upfront surgery be non-inferior compared to the group in the weight management program.
Sponsor: Benjamin T. Miller
You may qualify if…
- ✓ Adults having open retromuscular ventral hernia repair with an anticipated posterior component separation with transversus abdominis release and synthetic mesh
- ✓ BMI 40-55 kg/m2 and who are not planning to pursue weight loss surgery for any of the following reasons: they are not a candidate for weight loss surgery, cannot pursue weight loss surgery for insurance reasons, or are not interested in pursuing weight loss surgery.
You may not qualify if…
- ✕ Lack of English language fluency
- ✕ Urgent need for repair as determined by surgeon judgement
- ✕ Pregnant patients
- ✕ Permanent stoma in place
- ✕ Isolated flank hernia
- ✕ Anticipated need for staged operation; for example, patients who will undergo a mesh excision separate from definitive reconstruction.
- ✕ BMI \<40 or \>55 kg/m2
- ✕ Inability to participate in the Obesity Management Program due to lack of insurance coverage or history of mental illness (including eating disorders, schizophrenia, etc.).
Where it's recruiting
Source: ClinicalTrials.gov · NCT05925959 · last updated 2026-03-23