RecruitingThumb Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
Eligible age
40+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).
Sponsor: Mayo Clinic
You may qualify if…
- ✓ Adults \>40 years of age
- ✓ Pain at the thumb base brought on by direct pressure (grind test) and with movement
- ✓ Pain resistant to previous conservative management (including over the counter medications (ibuprofen/acetaminophen), icing, splinting/braces, or topical analgesics)
- ✓ Radiological observation indicative of arthritis based on the Eaton-Littler classification system (stages 1 through 4)
- ✓ Patient understands the protocol and signed the informed consent
- ✓ Patient is covered by health insurance
You may not qualify if…
- ✕ • Known allergy to either of the treatment products
- ✕ Patient's analgesic treatment regimen or other modalities of managing symptoms/pain associated with their hand pathology was modified within four weeks before trial inclusion
- ✕ Symptomatic Scaphoid-trapezial arthritis present
- ✕ Localized or systemic infection
- ✕ Previous thumb surgery on study thumb
- ✕ Previous thumb injury on study thumb
- ✕ Patient with inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis)
- ✕ Severe and/or uncontrolled hypertension
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT05992883 · last updated 2026-02-23