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RecruitingType 2 DiabetesInsulin ResistanceObesity

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

Eligible age

14–18 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents. The hypothesis of this study is that adolescents at risk for metabolic disease have enhanced MiMo related activities leading to insulin resistance.

Sponsor: University of Michigan

You may qualify if…

  • Between 14 and 18 years of age
  • Tanner stage 4 or 5 (mature adult stage of puberty)
  • Normal weight (BMI ≥ 5th percentile \& \< 85th percentile), overweight (BMI \> 86th percentile) \& \< 94th percentile), obese weight (BMI percentile ≥ 95th percentile), and/or pre-diabetes (HbA1c \> 5.7%)
  • For Type 2 Diabetes cohort, diagnosis of Type 2 Diabetes

You may not qualify if…

  • Currently pregnant
  • Use medications known to affect glucose metabolism (immunosuppressive medications, cancer medications, or high dose steroids), unless prescribed for Type 2 Diabetes management
  • Prior diagnosis of autoimmune disease, cancer, or a cognitive or perceptual disability that would inhibit following directions of study staff
  • Allergies or intolerance to milk, soy, or palm oil

Where it's recruiting

Michigan

Ann Arbor

Source: ClinicalTrials.gov · NCT06007404 · last updated 2026-06-03