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Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up

Eligible age

6–16 yrs

Accepts

All genders

Locations

2 states

Healthy volunteers

No

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About this study

The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring. This is an additional continuation of the Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) trial, to follow the offspring through 10 years of age. The hypothesis for this protocol is an extension of the VCSIP trial that supplemental vitamin C in pregnant smokers can significantly improve their children's airway function tests. The investigators aim to demonstrate sustained improvement in airway/pulmonary function and trajectory through 10 years of age.

Sponsor: Oregon Health and Science University

You may qualify if…

  • Women and their offspring randomized to vitamin C versus placebo during pregnancy as well as pregnant nonsmokers and their offspring enrolled as the reference group in the original VCSIP study

You may not qualify if…

  • participants who specifically withdraw consent

Where it's recruiting

Indiana

Indianapolis

Oregon

Portland

Source: ClinicalTrials.gov · NCT06106646 · last updated 2025-03-18