RecruitingType 2 Diabetes
Precision Dosing of Metformin in Youth With T2D
Eligible age
10–21 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).
Sponsor: University of California, San Francisco
You may qualify if…
- ✓ Age 10-21 years
- ✓ Provider diagnosis of T2D
- ✓ Stable medication regimen for 2 weeks before screening visit (No addition or removal of medications and no more than 20% change in insulin dose)
- ✓ ≥ 1 month from T2D diagnosis
- ✓ Taking regular metformin (not extended-release formula)
- ✓ Ability to wear CGM for a total of 6 weeks while in the study.
- ✓ English or Spanish speakers.
- ✓ Willing to abide by recommendations and study procedures.
You may not qualify if…
- ✕ Pancreatic autoantibody positivity (GAD-65, insulin, IA-2, ICA 512, Zn-T8).
- ✕ Known history of ongoing renal or hepatic disease.
- ✕ Known history of significant mental illness or developmental delay impacting the ability to complete study activities independently.
Where it's recruiting
California
Oakland · San Francisco
Source: ClinicalTrials.gov · NCT06120881 · last updated 2025-12-23