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RecruitingChronic Lymphocytic LeukemiaHematopoietic and Lymphoid System NeoplasmMantle Cell Lymphoma

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Eligible age

All ages

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This study evaluates the incidence and management of new and worsening high blood pressure in patients with B-cell cancers on BTKi treatment.

Sponsor: Mayo Clinic

You may qualify if…

  • Patients with chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), Waldenstrom macroglobulinemia (WM), and marginal zone lymphoma (MZL), planned to begin Bruton tyrosine kinase inhibitors (BTKi) treatment or who will start a new BTKi agent after a 5-day wash out period (either as a single agent or on combination with other chemotherapies), who are willing to return to Mayo Clinic for ongoing follow-up

You may not qualify if…

  • Patients with known central nervous system (CNS) involvement of their B-cell malignancy

Where it's recruiting

Minnesota

Rochester

Source: ClinicalTrials.gov · NCT06151730 · last updated 2026-02-27