RecruitingPrimary Progressive Aphasia
Communication Bridge 3 Study
Eligible age
18–100 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild-moderate Primary Progressive Aphasia (PPA). The aim of the study is to help us better understand the effects of speech-language therapy on communication abilities in individuals with PPA.
Sponsor: University of Chicago
You may qualify if…
- ✓ 1. Meets diagnostic criteria for PPA based on neurologist and supporting medical assessments (extracted from medical records)
- ✓ 2. English as primary language used in daily communication activities (by self-report)
- ✓ 3. Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report)
- ✓ 4. Adequate vision (aided or unaided) for reading a newspaper, or other functional materials (by self-report)
- ✓ 5. Able to pass technology screening and demonstrates sufficient knowledge for use of video conference and Communication Bridge™ web application use (with or without training)
- ✓ 6. Geriatric Depression Scale score ≤ 9
- ✓ 7. Mild-moderate PPA informed by a structured interview with a speech-language pathologist and a standardized testing battery.
- ✓ 1. 18+ years of age
You may not qualify if…
- ✕ A dementia diagnosis other than Primary Progressive Aphasia
- ✕ Participation is co-enrolled in an outside speech language therapy program during the study course.
- ✕ Communication partners will be excluded if they have a pre-existing communication impairment that would affect study participation (e.g., aphasia, dementia)
- ✕ Medical records will be requested and reviewed to determine eligibility
Where it's recruiting
Illinois
Chicago
Source: ClinicalTrials.gov · NCT06191198 · last updated 2026-06-01