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RecruitingHypertension, Pregnancy-Induced

Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

Eligible age

18+ yrs

Accepts

Women

Locations

2 states

Healthy volunteers

No

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About this study

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

Sponsor: Medical College of Wisconsin

You may qualify if…

  • Hypertensive disorders of pregnancy (HDP) diagnosis, specifically gestational hypertension, preeclampsia, eclampsia, or HELLP syndrome, according to ACOG guidelines
  • Postpartum day 0-4
  • Age ≥ 18 years
  • Able to communicate in English or in Spanish
  • Has an established OBGYN at an MCW or NU health system practice that has access to Epic electronic medical records.

You may not qualify if…

  • Pre-gestational hypertension
  • Type 1 or type 2 diabetes mellitus
  • Admitted to intensive care unit at the time of screening
  • Diagnosed with HDP during postpartum readmission after discharge from delivery hospitalization
  • Getting discharged on the day of screening
  • Known allergy or contraindication to nifedipine ER
  • Inability or unwillingness to provide informed consent
  • Already taking long-acting antihypertensive medication for standard care

Where it's recruiting

Illinois

Chicago

Wisconsin

Milwaukee

Source: ClinicalTrials.gov · NCT06220721 · last updated 2026-07-20

Reducing the Risk of Chronic Hypertension and Improving Vascular Funct · TrialPath