RecruitingEarly-stage Breast Cancer
Outcomes and Cosmesis With Whole Breast Irradiation and Boost
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This study is being done to evaluate cosmetic, patient-reported outcome measures (PROMs), and toxicities for women undergoing ultra-short whole breast irradiation (WBI) therapy with simultaneous integrated boost (SIB). 50 participants will be on study for up to 60 months.
Sponsor: University of Wisconsin, Madison
You may qualify if…
- ✓ Ability to understand and the willingness to sign a written informed consent document
- ✓ Histologically confirmed early stage (stage T1-T2) invasive carcinoma of the breast or DCIS
- ✓ Breast conserving surgery with negative margins and negative nodes (surgical axillary staging not mandatory), stage N0 or Nx
- ✓ Treatment plan should include breast conserving surgery and adjuvant whole breast irradiation (WBI) therapy delivered with 3D-CRT or IMRT techniques
- ✓ Treatment plan includes breast tumor bed boost
- ✓ Willingness to comply with all study procedures and be available for the duration of the study
You may not qualify if…
- ✕ Mastectomy of ipsilateral breast
- ✕ Lack of histologic diagnosis
- ✕ Histologic involvement of the axillary or regional nodes or metastatic disease
- ✕ Accelerated partial breast irradiation treatment plan
- ✕ Previous history of non-breast malignancy diagnosed in the past 5 years except for basal or squamous cell cancer of the skin
- ✕ Previous history of chest radiation therapy
- ✕ Previous history of ipsilateral breast cancer
- ✕ Concurrent cytotoxic chemotherapy
Where it's recruiting
Wisconsin
Madison
Source: ClinicalTrials.gov · NCT06295744 · last updated 2026-06-10