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RecruitingKnee OsteoarthritisKnee ArthropathySurgery

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

Eligible age

18–80 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline mental health and poor physical function, improves satisfaction at 1-year (when compared to standard of care).

Sponsor: The Cleveland Clinic

You may qualify if…

  • 1. Adult subject (Age \>18 and \< 80 years of age)
  • 2. The subject is proficient in the English language
  • 3. The patient is voluntarily prepared to sign the 'Informed Consent Form'
  • 4. The patient is scheduled for a unilateral primary TKA
  • 5. TKA PROMs Phenotypes with higher risk of dissatisfaction
  • 6. Patient is willing and able to complete the protocol required follow-up

You may not qualify if…

  • 1. Patient requires simultaneous or staged bilateral knee replacements, staged \<90 days apart
  • 2. Patients undergoing revision TKA
  • 3. Inflammatory arthritis
  • 4. History of infection in the joint undergoing TKA
  • 5. Patient is considered a member of a protected population (e.g., prisoner, mentally incompetent, etc.)

Where it's recruiting

Ohio

Cleveland

Source: ClinicalTrials.gov · NCT06298721 · last updated 2026-06-11